Iron-Responsive Element Binding Protein 2 (IREB2) Peptide
IREB2
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN978591
发货至:
中国
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Contact Info
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中国
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Quick Overview for Iron-Responsive Element Binding Protein 2 (IREB2) Peptide (ABIN978591)
抗原
IREB2
(Iron-Responsive Element Binding Protein 2 (IREB2))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-IREB2 antibody (Catalog #: ARP40509_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
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背景
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IREB2 binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. IREB2 binds to the IRE element in ferritin which results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
Alias Symbols: ACO3, FLJ23381, IRP2, IRP2AD
Protein Interaction Partner: YBX1,YBX1,YBX1
Protein Size: 963 -
分子量
- 105 kDa
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基因ID
- 3658
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NCBI登录号
- NM_004136, NP_004127
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UniProt
- P48200
抗原
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