Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B) Peptide
INPP5B
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN978558
发货至:
中国
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Contact Info
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中国
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北京 101111
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Quick Overview for Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B) Peptide (ABIN978558)
抗原
INPP5B
(Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-INPP5B antibody (Catalog #: ARP54772_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- INPP5B (Inositol Polyphosphate-5-Phosphatase, 75kDa (INPP5B))
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背景
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Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). INPP5B is the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus.Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Alias Symbols: 5PTase, MGC65156, MGC71303
Protein Interaction Partner: SMURF1
Protein Size: 913 -
分子量
- 77 kDa
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基因ID
- 3633
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NCBI登录号
- NM_005540, NP_005531
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UniProt
- P32019
抗原
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