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Inhibitor of Growth Family, Member 1 (ING1) Peptide

ING1 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN978547
发货至: 中国
  • 抗原 See all ING1 products
    ING1 (Inhibitor of Growth Family, Member 1 (ING1))
    宿主
    资源
    • 2
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-ING1 antibody (Catalog #: ARP50512_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    ING1 (Inhibitor of Growth Family, Member 1 (ING1))
    背景
    ING1 is a tumor suppressor protein that can induce cell growth arrest and apoptosis. The protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of ING1 gene have been detected in various cancers.This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

    Alias Symbols: p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a

    Protein Interaction Partner: TP53,BRMS1,BRMS1L,C20orf20,DMAP1,EP300,HDAC1,HDAC2,KAT2B,PCNA,RBBP4,RBBP7,RBP1,SAP30,SFN,SIN3A,TP53,YWHAB,YWHAE,YWHAG,YWHAH,YWHAQ,YWHAZ,ACTL6A,ARID1A,CREBBP,DMAP1,EP300,HDAC1,HDAC2,HHT1,HHT2,HIST2H3A,HIST4H4,KAT2B,PCNA,RBBP4,RBBP7,SAP30,SIN3A,SMARCA4,SMARCB1,SMARCC1,SMARCC2,SMARCD1,TP53,TRRAP

    Protein Size: 279
    分子量
    32 kDa
    基因ID
    3621
    NCBI登录号
    NM_198219, NP_937862
    UniProt
    Q5T9H0
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