IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) Peptide
IMPDH2
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN978541
发货至:
中国
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Contact Info
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Quick Overview for IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2) Peptide (ABIN978541)
抗原
IMPDH2
(IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-IMPDH2 antibody (Catalog #: ARP54366_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IMPDH2 (IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))
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背景
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IMPDH2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. It catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. IMPDH2 is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: IMPD2, IMPDH-II
Protein Interaction Partner: AKT1,AKT1,PIAS4,SUMO4,UBQLN4,AKT1,ATG5,BCAR3,IKBKE,VHL
Protein Size: 514 -
分子量
- 56 kDa
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基因ID
- 3615
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NCBI登录号
- NM_000884, NP_000875
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UniProt
- P12268
抗原
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