Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA) (N-Term) Peptide
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Quick Overview for Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA) (N-Term) Peptide (ABIN978504)
抗原
宿主
资源
应用范围
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蛋白结构域
- N-Term
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产品特性
- This is a synthetic peptide designed for use in combination with anti-IL28RA antibody (Catalog #: ARP48069_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IL28RA (Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA))
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背景
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IL28RA belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: CRF2/12, IFNLR, IFNLR1, LICR2, il-28r1, IL-28R1, IL28RA
Protein Interaction Partner: IL28A,IL28RA,IL29,NAA38,NAA38
Protein Size: 491 -
分子量
- 54 kDa
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基因ID
- 163702
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NCBI登录号
- NM_173064, NP_775087
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UniProt
- Q5VTX8
抗原
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