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Interleukin 1, beta (IL1B) (N-Term) Peptide

IL1B 适用: 人 宿主: 合成 BP, WB, IHC
产品编号 ABIN978485
发货至: 中国
  • 抗原 See all IL-1 beta (IL1B) products
    IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
    蛋白结构域
    N-Term
    宿主
    资源
    • 11
    • 1
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    MAEVPELASE MMAYYSGNED DLFFEADGPK QMKCSFQDLD LCPLDGGIQL
    产品特性
    This is a synthetic peptide designed for use in combination with anti-IL1B Antibody(ARP54323_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
    别名
    IL-1 Peptide, IL1-BETA Peptide, IL1F2 Peptide, IL-1BETA Peptide, IL1beta Peptide, il1-b Peptide, zgc:111873 Peptide, IL-1B Peptide, IL-1beta Peptide, Il-1b Peptide, IL1B Peptide, IL-1 beta Peptide, IL-1b Peptide, interleukin 1 beta Peptide, interleukin 1, beta Peptide, IL1B Peptide, il1b Peptide, Il1b Peptide
    背景
    IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. The gene encoding IL1B and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

    Alias Symbols: IL-1, IL1-BETA, IL1F2

    Protein Interaction Partner: A2M,ADRB2,CASP1,CASP4,IL1B,IL1R1,IL1R2,IL1RAP,MMP2,PRTN3,IL1R1,MAPK8IP2,UBE2N,ZNF675

    Protein Size: 269
    分子量
    17 kDa
    基因ID
    3553
    NCBI登录号
    NM_000576, NP_000567
    UniProt
    P01584
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