Interleukin 10 Receptor, alpha (IL10RA) Peptide
IL10RA
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN978469
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Quick Overview for Interleukin 10 Receptor, alpha (IL10RA) Peptide (ABIN978469)
抗原
IL-10RA (IL10RA)
(Interleukin 10 Receptor, alpha (IL10RA))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-IL10RA antibody (Catalog #: ARP45135_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
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背景
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IL10RA is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.
Alias Symbols: CDW210A, HIL-10R, IL-10R1, IL10R, CD210, CD210a
Protein Interaction Partner: JAK1,IL10,IL10RB,JAK1,IL10,IL10RB,JAK1
Protein Size: 578 -
分子量
- 61 kDa
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基因ID
- 3587
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NCBI登录号
- NM_001558, NP_001549
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UniProt
- Q13651
抗原
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