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Immunoglobulin Superfamily, Member 8 (IGSF8) (Middle Region) Peptide

IGSF8 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN978453
发货至: 中国
  • 抗原 See all IGSF8 products
    IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 2
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    LAVEAGAPYA ERLAAGELRL GKEGTDRYRM VVGGAQAGDA GTYHCTAAEW
    产品特性
    This is a synthetic peptide designed for use in combination with anti-IGSF8 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))
    背景
    IGSF8 may play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. IGSF8 may also play a role on integrin-dependent morphology and motility functions. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.

    Alias Symbols: CD316, CD81P3, EWI2, PGRL, EWI-2, KCT-4, LIR-D1

    Protein Size: 613
    分子量
    65 kDa
    基因ID
    93185
    NCBI登录号
    NM_052868, NP_443100
    UniProt
    Q969P0
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