Islet Amyloid Polypeptide (IAPP) (N-Term) Peptide
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Quick Overview for Islet Amyloid Polypeptide (IAPP) (N-Term) Peptide (ABIN978369)
抗原
宿主
资源
应用范围
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蛋白结构域
- N-Term
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序列
- MGILKLQVFL IVLSVALNHL KATPIESHQV EKRKCNTATC ATQRLANFLV
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产品特性
- This is a synthetic peptide designed for use in combination with anti-IAPP Antibody(ARP41728_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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Islet Amyloid Polypeptide (IAPP) peptide (Ovalbumin)
IAPP 适用: 小鼠 宿主: 合成 WB, Imm, SDS
Islet Amyloid Polypeptide (IAPP) peptide (Ovalbumin)IAPP 适用: 人 宿主: 合成 WB, Imm, SDS
Islet Amyloid Polypeptide (IAPP) peptide (BSA)IAPP 适用: 大鼠 宿主: 合成 WB, Imm, SDS
Islet Amyloid Polypeptide (IAPP) peptide (BSA)IAPP 适用: 小鼠 宿主: 合成 WB, Imm, SDS
Islet Amyloid Polypeptide (IAPP) peptide (BSA)IAPP 适用: 人 宿主: 合成 WB, Imm, SDS
Islet Amyloid Polypeptide (IAPP) peptide (Ovalbumin)IAPP 适用: 大鼠 宿主: 合成 WB, Imm, SDS
Islet Amyloid Polypeptide (IAPP) peptide (Ovalbumin)IAPP 适用: 人 宿主: 合成 WB, Imm, SDS
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))
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背景
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Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
Alias Symbols: AMYLIN, DAP, IAP
Protein Interaction Partner: COL25A1,PCSK1,PCSK2,PDX1,RAMP1,RAMP2
Protein Size: 89 -
分子量
- 4 kDa
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基因ID
- 3375
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NCBI登录号
- NM_000415, NP_000406
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UniProt
- P10997
抗原
-
