Heat Shock 22kDa Protein 8 (HSPB8) (Middle Region) Peptide
HSPB8
适用: 人
宿主: 合成
BP, WB
Quick Overview for Heat Shock 22kDa Protein 8 (HSPB8) (Middle Region) Peptide (ABIN978319)
抗原
HSPB8
(Heat Shock 22kDa Protein 8 (HSPB8))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
-
-
蛋白结构域
- Middle Region
-
序列
- PEELMVKTKD GYVEVSGKHE EKQQEGGIVS KNFTKKIQLP AEVDPVTVFA
-
产品特性
- This is a synthetic peptide designed for use in combination with anti-HSPB8 Antibody(ARP55036_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
纯化方法
- Purified
-
-
-
-
应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
浓度
- 1 mg/mL
-
缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
-
背景
-
HSPB8 belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of HSPB8 protein is induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, HSPB8 appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in the encoding HSPB8 gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
Alias Symbols: CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22
Protein Interaction Partner: HSPB1,HSPB8,BAG3,CSNK2A1,HSPB1,HSPB6,HSPB7,HSPB8,MAPK3,PRKCA,BAG3,HSPB1,HSPB2,HSPB7,HSPB8
Protein Size: 196 -
分子量
- 21 kDa
-
基因ID
- 26353
-
NCBI登录号
- NM_014365, NP_055180
-
UniProt
- Q9UJY1
抗原
-
You are here:
