Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL) Peptide
HNRNPL
适用: 人
宿主: 合成
BP, WB, IHC, IF, IP
Quick Overview for Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL) Peptide (ABIN978116)
抗原
HNRNPL
(Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-HNRPL antibody (Catalog #: ARP40368_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))
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背景
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Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions.Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: HNRPL, hnRNP-L, P/OKcl.14
Protein Interaction Partner: GSTZ1,HNRNPK,PTBP1,SLC2A2,APEX1,CSE1L,FGFR3,HMG20B,HNRNPA2B1,HNRNPK,HNRNPL,PCBP2,PJA1,PTBP1,SUMO4,APEX1,CSE1L,DOCK4,EIF2B1,FGFR3,HMG20B,HNRNPA1,HNRNPA2B1,HNRNPK,HNRNPL,KHDRBS2,Khdrbs3,PCBP2,PTBP1,PUF60,YWHAZ
Protein Size: 589 -
分子量
- 65 kDa
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基因ID
- 3191
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NCBI登录号
- NM_001533, NP_001524
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UniProt
- P14866
抗原
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