Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD) Peptide
HNRNPD
适用: 人
宿主: 合成
BP, WB, IHC
产品编号 ABIN978105
发货至:
中国
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Contact Info
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中国
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北京 101111
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Quick Overview for Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD) Peptide (ABIN978105)
抗原
HNRNPD/AUF1 (HNRNPD)
(Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-HNRPD antibody (Catalog #: ARP40238_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))
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背景
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HNRPD belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.
Alias Symbols: P37, AUF1, AUF1A, HNRPD, hnRNPD0
Protein Interaction Partner: SAFB,SAFB,CSDE1,EXOSC4,GSK3B,HNRNPD,IGF2BP2,LDHA,LSM5,PABPC1,PCBP1,PCBP2,PCSK7,PRKACA,SAFB,SFN,SFRS12,SUMO4,SYNCRIP,TNPO1,UBE2I,YBX1,CDK9,EIF4G1,GPN1,HNRNPD,HNRNPH1,HSPA4,HSPA8,HSPB1,KHDRBS2,LSM5,MEPCE,SAFB,TRNAN1
Protein Size: 355 -
分子量
- 39 kDa
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基因ID
- 3184
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NCBI登录号
- NM_031370, NP_112738
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UniProt
- Q14103
抗原
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