Hepatocyte Nuclear Factor 4, alpha (HNF4A) (Middle Region) Peptide
HNF4A
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN978084
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Quick Overview for Hepatocyte Nuclear Factor 4, alpha (HNF4A) (Middle Region) Peptide (ABIN978084)
抗原
HNF4A
(Hepatocyte Nuclear Factor 4, alpha (HNF4A))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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产品特性
- This is a synthetic peptide designed for use in combination with anti-HNF4A antibody (Catalog #: ARP45595_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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Hepatocyte Nuclear Factor 4, alpha (HNF4A) peptide
HNF4A 适用: 人, Pig, 犬 宿主: 合成 BP, Imm
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))
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背景
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The protein encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants.
Alias Symbols: FLJ39654, HNF4, HNF4a7, HNF4a8, HNF4a9, MODY, MODY1, NR2A1, NR2A21, TCF, TCF14, HNF4alpha
Protein Interaction Partner: CREBBP,ELP3,H3F3A,SMARCA4,COPS5,CREBBP,ESR1,FOXO1,HNF1A,HNF4A,MAPK14,MECR,MED1,MED14,NCOA1,NCOA2,NCOA6,NPPA,NR0B2,NR2C2,NR2F1,NRBF2,NRIP1,PNRC1,PNRC2,PPARGC1A,PPARGC1B,PRKAA2,PROX1,SIRT1,SMAD2,SMAD3,SMAD4,SP1,SREBF2,SUB1,TP53,TRIM24,UBE2I,ZNHIT3,AR,CREBBP,CTNNB1,EXT2,FOXO1,MED1,MED10,MED14,MED16,MED17,MED21,MED23,MED24,MED7,NCOA1,NCOA2,NR0B2,NR2C2,PABPC4,PPARGC1B,RAD50,SNCG,STK16,SUB1,TP53,ZNHIT3
Protein Size: 442 -
分子量
- 49 kDa
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基因ID
- 3172
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NCBI登录号
- NM_001030003, NP_001025174
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UniProt
- P41235
抗原
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