High Mobility Group AT-Hook 1 (HMGA1) (N-Term) Peptide
HMGA1
适用: 人
宿主: 合成
BP, WB
Quick Overview for High Mobility Group AT-Hook 1 (HMGA1) (N-Term) Peptide (ABIN978048)
抗原
HMGA1
(High Mobility Group AT-Hook 1 (HMGA1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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序列
- MSESSSKSSQ PLASKQEKDG TEKRGRGRPR KQPPKEPSEV PTPKRPRGRP
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产品特性
- This is a synthetic peptide designed for use in combination with anti-HMGA1 Antibody(ARP38111_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))
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背景
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This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: HMG-R, HMGA1A, HMGIY, MGC12816, MGC4242, MGC4854
Protein Interaction Partner: ATF2,CDK1,CEBPB,CREBBP,CSNK2A1,CSNK2A2,ELF1,EWSR1,HIPK2,IRF1,JUN,NFYA,POU3F1,PPARG,PRMT6,RARG,RNF4,RXRA,SP1,SRF,SUFU,ATF2,BANF1,CEBPB,CHD1,ELF1,EWSR1,INSR,IRF1,JUN,NFYA,NPM1,PARP1,POU3F1,PPARG,PRMT6,SP1
Protein Size: 96 -
分子量
- 11 kDa
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基因ID
- 3159
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NCBI登录号
- NM_002131, NP_002122
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UniProt
- Q5T6U8
抗原
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