Hexosaminidase A (HEXA) (C-Term) Peptide
HEXA
适用: 人
宿主: 合成
BP, IHC, WB
Quick Overview for Hexosaminidase A (HEXA) (C-Term) Peptide (ABIN977949)
抗原
Hexosaminidase A (HEXA)
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- WKDFYIVEPL AFEGTPEQKA LVIGGEACMW GEYVDNTNLV PRLWPRAGAV
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产品特性
- This is a synthetic peptide designed for use in combination with anti-HEXA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Hexosaminidase A (HEXA)
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背景
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This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).
Alias Symbols: MGC99608, TSD
Protein Interaction Partner: GM2A,GM2A,USP22
Protein Size: 529 -
分子量
- 48 kDa
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基因ID
- 3073
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NCBI登录号
- NM_000520, NP_000511
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UniProt
- P06865
抗原
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