Histone Deacetylase 3 (HDAC3) (C-Term) Peptide
HDAC3
适用: 大鼠
宿主: 合成
BP, WB
产品编号 ABIN977905
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Quick Overview for Histone Deacetylase 3 (HDAC3) (C-Term) Peptide (ABIN977905)
抗原
HDAC3
(Histone Deacetylase 3 (HDAC3))
宿主
大鼠
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- DVPADLLTYD RTDEADAEER GPEENYSRPE APNEFYDGDH DNDKESDVEI
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产品特性
- This is a synthetic peptide designed for use in combination with anti-Hdac3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HDAC3 (Histone Deacetylase 3 (HDAC3))
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背景
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Hdac3 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.Hdac3 is required to repress transcription of the POU1F1 transcription factor. Hdac3 acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation.
Alias Symbols: Hdac3
Protein Interaction Partner: Hr
Protein Size: 428 -
分子量
- 49 kDa
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基因ID
- 84578
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NCBI登录号
- NM_053448, NP_445900
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UniProt
- Q6P6W3
抗原
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