Hemoglobin, gamma G (HBG2) (Middle Region) Peptide
HBG2
适用: 人
宿主: 合成
WB, BP
产品编号 ABIN977868
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Quick Overview for Hemoglobin, gamma G (HBG2) (Middle Region) Peptide (ABIN977868)
抗原
HBG2
(Hemoglobin, gamma G (HBG2))
宿主
人
资源
合成
应用范围
Western Blotting (WB), Blocking Peptide (BP)
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蛋白结构域
- Middle Region
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序列
- MGNPKVKAHG KKVLTSLGDA IKHLDDLKGT FAQLSELHCD KLHVDPENFK
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产品特性
- This is a synthetic peptide designed for use in combination with anti-HBG2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HBG2 (Hemoglobin, gamma G (HBG2))
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背景
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The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
Alias Symbols: FLJ76540
Protein Interaction Partner: CYB5R3,HBB,HBG2,SMAD5,HBG2
Protein Size: 147 -
分子量
- 16 kDa
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基因ID
- 3048
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NCBI登录号
- NM_000184, NP_000175
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UniProt
- P69892
抗原
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