HCLS1 Associated Protein X-1 (HAX1) (Middle Region) Peptide
HAX1
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all HAX1 products
- HAX1 (HCLS1 Associated Protein X-1 (HAX1))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-HAX1 antibody (Catalog #: ARP52141_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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HCLS1 Associated Protein X-1 (HAX1) peptide
HAX1 适用: 人 宿主: 合成 BP, Imm
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- HAX1 (HCLS1 Associated Protein X-1 (HAX1))
- 背景
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HAX1 is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease.The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: HCLSBP1, HS1BP1, SCN3
Protein Interaction Partner: HCLS1,IL1A,IQGAP2,ABCB1,ABCB11,ABCB4,CTTN,DGKD,EIF3F,HCLS1,IL1A,KIAA0513,PKD2,YWHAQ,DGKD,EIF3F,IL1A
Protein Size: 279 - 分子量
- 31 kDa
- 基因ID
- 10456
- NCBI登录号
- NM_006118, NP_006109
- UniProt
- O00165
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