Heart and Neural Crest Derivatives Expressed 2 (HAND2) (C-Term) Peptide
HAND2
适用: 小鼠
宿主: 合成
BP, WB
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- 抗原 See all HAND2 products
- HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))
- 蛋白结构域
- C-Term
- 宿主
- 小鼠
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- DQNGEAEAFK AEIKKTDVKE EKRKKELNEI LKSTVSSNDK KTKGRTGWPQ
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-Hand2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))
- 背景
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Hand2 is essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. It is required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. It plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Hand2 is involved in the development of branchial arches, which give rise to unique structures in the head and neck.
Alias Symbols: AI225906, AI661148, Ehand2, Hed, Th2, Thing2, bHLHa26, dHAND
Protein Interaction Partner: Hand1,Twist1
Protein Size: 217 - 分子量
- 24 kDa
- 基因ID
- 15111
- NCBI登录号
- NM_010402, NP_034532
- UniProt
- Q61039
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