H2A Histone Family, Member Y2 (H2AFY2) (Middle Region) Peptide
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Quick Overview for H2A Histone Family, Member Y2 (H2AFY2) (Middle Region) Peptide (ABIN977826)
抗原
宿主
资源
应用范围
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蛋白结构域
- Middle Region
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序列
- PRIHPELLAK KRGTKGKSET ILSPPPEKRG RKATSGKKGG KKSKAAKPRT
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产品特性
- This is a synthetic peptide designed for use in combination with anti-H2AFY2 Antibody(ARP57281_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- H2AFY2 (H2A Histone Family, Member Y2 (H2AFY2))
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背景
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H2AFY2 is the variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. H2AFY2 may be involved in stable X chromosome inactivation.
Alias Symbols: macroH2A2
Protein Interaction Partner: tat
Protein Size: 372 -
分子量
- 40 kDa
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基因ID
- 55506
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NCBI登录号
- NM_018649, NP_061119
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UniProt
- Q9P0M6
抗原
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