GRB2-Related Adaptor Protein (GRAP) (Middle Region) Peptide
GRAP
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN977661
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Quick Overview for GRB2-Related Adaptor Protein (GRAP) (Middle Region) Peptide (ABIN977661)
抗原
GRAP
(GRB2-Related Adaptor Protein (GRAP))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- KRQIFLRDEE PLLKSPGACF AQAQFDFSAQ DPSQLSFRRG DIIEVLERPD
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产品特性
- This is a synthetic peptide designed for use in combination with anti-GRAP Antibody(ARP52210_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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GRB2-Related Adaptor Protein (GRAP) peptide
GRAP 适用: 人, 大鼠, Cow, 小鼠 宿主: 合成 BP, Imm
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GRAP (GRB2-Related Adaptor Protein (GRAP))
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背景
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This gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain.
Alias Symbols: MGC64880
Protein Interaction Partner: ARHGAP32,ARHGAP32,EPOR,FASLG,FYN,KHDRBS1,KIT,LAT,LCK,PLCG1,SHC1,SOS1,EPOR,FASLG,GAB2,KIT,LAT,SOS1
Protein Size: 217 -
分子量
- 25 kDa
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基因ID
- 10750
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NCBI登录号
- NM_006613, NP_006604
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UniProt
- Q13588
抗原
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