GM2 Ganglioside Activator (GM2A) (N-Term) Peptide
GM2A
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN977489
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Quick Overview for GM2 Ganglioside Activator (GM2A) (N-Term) Peptide (ABIN977489)
抗原
GM2A
(GM2 Ganglioside Activator (GM2A))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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序列
- SWDNCDEGKD PAVIRSLTLE PDPIIVPGNV TLSVMGSTSV PLSSPLKVDL
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产品特性
- This is a synthetic peptide designed for use in combination with anti-GM2A Antibody(ARP46007_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GM2A (GM2 Ganglioside Activator (GM2A))
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背景
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This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
Alias Symbols: SAP-3, GM2-AP
Protein Interaction Partner: GPLD1,HEXA,PLD2,HEXA
Protein Size: 193 -
分子量
- 18 kDa
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基因ID
- 2760
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NCBI登录号
- NM_000405, NP_000396
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UniProt
- P17900
抗原
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