Glucosidase, Beta, Acid (GBA) (C-Term) Peptide
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Quick Overview for Glucosidase, Beta, Acid (GBA) (C-Term) Peptide (ABIN977306)
抗原
宿主
资源
应用范围
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蛋白结构域
- C-Term
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序列
- EGSQRVGLVA SQKNDLDAVA LMHPDGSAVV VVLNRSSKDV PLTIKDPAVG
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产品特性
- This is a synthetic peptide designed for use in combination with anti-GBA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GBA (Glucosidase, Beta, Acid (GBA))
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背景
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This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Alias Symbols: GBA1, GCB, GLUC
Protein Size: 536 -
分子量
- 59 kDa
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基因ID
- 2629
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NCBI登录号
- NM_000157, NP_000148
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UniProt
- P04062
抗原
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