Carbohydrate (N-Acetylgalactosamine 4-Sulfate 6-O) Sulfotransferase 15 (CHST15) Peptide
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Quick Overview for Carbohydrate (N-Acetylgalactosamine 4-Sulfate 6-O) Sulfotransferase 15 (CHST15) Peptide (ABIN977248)
抗原
宿主
资源
应用范围
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产品特性
- This is a synthetic peptide designed for use in combination with anti-GALNAC4S-6ST antibody (Catalog #: ARP47193_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CHST15 (Carbohydrate (N-Acetylgalactosamine 4-Sulfate 6-O) Sulfotransferase 15 (CHST15))
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背景
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GALNAC4S-6ST is a sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO(4)) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. GALNAC4S-6ST may also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression, however such results are unclear in vivo.
Alias Symbols: BRAG, DKFZp781H1369, KIAA0598, MGC34346, RP11-47G11.1, GALNAC4S-6ST
Protein Interaction Partner: HCK,LYN,RRAGD,HCK
Protein Size: 561 -
分子量
- 65 kDa
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基因ID
- 51363
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NCBI登录号
- NM_015892, NP_056976
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UniProt
- Q7LFX5
抗原
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