gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) Peptide
GABRG2
适用: 人
宿主: 合成
BP, WB
Quick Overview for gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) Peptide (ABIN977221)
抗原
GABRG2
(gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-GABRG2 antibody (Catalog #: ARP35574_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GABRG2 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2))
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背景
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Gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain, mediates neuronal inhibition by binding to GABA receptors. The type A GABA receptors are pentameric chloride channels assembled from among many genetic variants of GABA(A) subunits. GABRG2 is the gamma 2 subunit of GABA(A) receptor. Mutations in this gene have been associated with epilepsy and febrile seizures.Gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain, mediates neuronal inhibition by binding to GABA receptors. The type A GABA receptors are pentameric chloride channels assembled from among many genetic variants of GABA(A) subunits. This gene encodes the gamma 2 subunit of GABA(A) receptor. Mutations in this gene have been associated with epilepsy and febrile seizures. Alternative splicing of this gene results in transcript variants encoding different isoforms.
Alias Symbols: CAE2, ECA2, GEFSP3
Protein Interaction Partner: DRD5,GABARAP,GABRG2,PPP3CA,PRKCA,PRKCB,ZDHHC3,DRD5,GABARAP
Protein Size: 327 -
分子量
- 36 kDa
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基因ID
- 2566
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NCBI登录号
- NM_198903, NP_944493
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UniProt
- P18507
抗原
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