Fibroblast Growth Factor Receptor Substrate 3 (FRS3) (Middle Region) Peptide
FRS3
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all FRS3 products
- FRS3 (Fibroblast Growth Factor Receptor Substrate 3 (FRS3))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-FRS3 antibody (Catalog #: ARP52228_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- FRS3 (Fibroblast Growth Factor Receptor Substrate 3 (FRS3))
- 背景
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FRS3 is an adapter protein that links FGR and NGF receptors to downstream signaling pathways. FRS3 is involved in the activation of MAP kinases. FRS3 down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.The protein encoded by this gene is a substrate for the fibroblast growth factor receptor. It is found in peripheral plasma membrane and functions in linking FGF receptor stimulation to activators of Ras. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FRS2B, FRS2beta, MGC17167, SNT-2, SNT2
Protein Interaction Partner: FGFR1,NTRK1,PRKCI,BMPR2,FGFR1,GRB2,KARS,MAPK1,NTRK1,NTRK2,PRKCI,PTPN11,RND1,BMPR2,FGFR1
Protein Size: 492 - 分子量
- 54 kDa
- 基因ID
- 10817
- NCBI登录号
- NM_006653, NP_006644
- UniProt
- O43559
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