Forkhead Box O4 (FOXO4) (C-Term) Peptide
FOXO4
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all FOXO4 products
- FOXO4 (Forkhead Box O4 (FOXO4))
- 蛋白结构域
- C-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- TPVLTPPTEA ASQDRMPQDL DLDMYMENLE CDMDNIISDL MDEGEGLDFN
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-FOXO4 Antibody(ARP32110_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- FOXO4 (Forkhead Box O4 (FOXO4))
- 背景
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FOXO4 is transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. The protein can down-regulate expression of HIF1A and suppress hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle. A chromosomal aberration involving FOXO4 is found in acute leukemias.
Alias Symbols: AFX, AFX1, MGC120490, MLLT7
Protein Interaction Partner: AKT1,CCND1,CDKN1A,CTNNB1,FOXG1,SMAD3,SMAD4,AKT1,AKT2,CREBBP,CTNNB1,ESR1,FOXG1,SMAD3,SMAD4,XPO1,YWHAZ,CREBBP,CTNNB1,ESR1,MDM2,PIN1,SMAD3,SMAD4,UBC,USP7,XPO1
Protein Size: 505 - 分子量
- 54 kDa
- 基因ID
- 4303
- NCBI登录号
- NM_005938, NP_005929
- UniProt
- P98177
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