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Forkhead Box A2 (FOXA2) (Middle Region) Peptide

FOXA2 适用: 小鼠 宿主: 合成 BP, WB
产品编号 ABIN976981
发货至: 中国
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Quick Overview for Forkhead Box A2 (FOXA2) (Middle Region) Peptide (ABIN976981)

抗原

FOXA2 (Forkhead Box A2 (FOXA2))

宿主

小鼠

资源

  • 6
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB)
  • 蛋白结构域

    Middle Region

    序列

    SSGGKKTAPG SQASQAQLGE AAGSASETPA GTESPHSSAS PCQEHKRGGL

    产品特性

    This is a synthetic peptide designed for use in combination with anti-Foxa2 Antibody(ARP37060_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    纯化方法

    Purified
  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    浓度

    1 mg/mL

    缓冲液

    Final peptide concentration is 1 mg/mL in PBS.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    FOXA2 (Forkhead Box A2 (FOXA2))

    背景

    Foxa2 is a transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues.Foxa2 is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites.Foxa2 binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3'. In embryonic development Foxa2 is required for notochord formation.Foxa2 is involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs.

    Alias Symbols: HNF3-beta, HNF3beta, Hnf-3b, Hnf3b, Tcf-3b, Tcf3b

    Protein Interaction Partner: Acadm,Acadvl,Gck,Hnf4a,Igfbp1,Pklr,Ucp2

    Protein Size: 459

    分子量

    48 kDa

    基因ID

    15376

    NCBI登录号

    NM_010446, NP_034576

    UniProt

    P35583
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