Forkhead Box A2 (FOXA2) (Middle Region) Peptide
FOXA2
适用: 小鼠
宿主: 合成
BP, WB
Quick Overview for Forkhead Box A2 (FOXA2) (Middle Region) Peptide (ABIN976981)
抗原
FOXA2
(Forkhead Box A2 (FOXA2))
宿主
小鼠
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- SSGGKKTAPG SQASQAQLGE AAGSASETPA GTESPHSSAS PCQEHKRGGL
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产品特性
- This is a synthetic peptide designed for use in combination with anti-Foxa2 Antibody(ARP37060_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FOXA2 (Forkhead Box A2 (FOXA2))
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背景
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Foxa2 is a transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues.Foxa2 is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites.Foxa2 binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3'. In embryonic development Foxa2 is required for notochord formation.Foxa2 is involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs.
Alias Symbols: HNF3-beta, HNF3beta, Hnf-3b, Hnf3b, Tcf-3b, Tcf3b
Protein Interaction Partner: Acadm,Acadvl,Gck,Hnf4a,Igfbp1,Pklr,Ucp2
Protein Size: 459 -
分子量
- 48 kDa
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基因ID
- 15376
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NCBI登录号
- NM_010446, NP_034576
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UniProt
- P35583
抗原
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