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Fragile X Mental Retardation 1 (FMR1) (C-Term) Peptide

FMR1 适用: 大鼠 宿主: 合成 BP, WB
产品编号 ABIN976953
发货至: 中国
  • 抗原 See all FMR1 products
    FMR1 (Fragile X Mental Retardation 1 (FMR1))
    蛋白结构域
    C-Term
    宿主
    大鼠
    资源
    • 7
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    QIGASSRPPP NRTDKEKGYV TDDGQGMGRG SRPYRNRGHG RRGPGYTSES
    产品特性
    This is a synthetic peptide designed for use in combination with anti-Fmr1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    FMR1 (Fragile X Mental Retardation 1 (FMR1))
    背景
    Fmr1 is a translation repressor. Fmr1 is a component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression. RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs.Fmr1 is associated with polysomes. Fmr1 is involved in the transport of mRNA from the nucleus to the cytoplasm. Fmr1 binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C).

    Alias Symbols: FMRP, Fmr1

    Protein Size: 593
    分子量
    67 kDa
    基因ID
    24948
    NCBI登录号
    NM_052804, NP_434691
    UniProt
    Q80WE1
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