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FK506 Binding Protein 3, 25kDa (FKBP3) Peptide

FKBP3 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN976872
发货至: 中国

Quick Overview for FK506 Binding Protein 3, 25kDa (FKBP3) Peptide (ABIN976872)

抗原

FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))

宿主

资源

  • 1
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB)
  • 产品特性

    This is a synthetic peptide designed for use in combination with anti-FKBP3 antibody (Catalog #: ARP54612_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    纯化方法

    Purified
  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    浓度

    1 mg/mL

    缓冲液

    Final peptide concentration is 1 mg/mL in PBS.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))

    背景

    FKBP3 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP3 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.

    Alias Symbols: FKBP-25, PPIase, FKBP-3, FKBP25

    Protein Interaction Partner: CSNK2A1,CSNK2A2,CSNK2B,HDAC1,HDAC2,YY1,HDAC1,HDAC2,MDM2,MTA2,TP53,YY1

    Protein Size: 224

    分子量

    25 kDa

    基因ID

    2287

    NCBI登录号

    NM_002013, NP_002004

    UniProt

    Q00688
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