FK506 Binding Protein 1A, 12kDa (FKBP1A) (N-Term) Peptide
FKBP1A
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN976870
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for FK506 Binding Protein 1A, 12kDa (FKBP1A) (N-Term) Peptide (ABIN976870)
抗原
FKBP1A
(FK506 Binding Protein 1A, 12kDa (FKBP1A))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
-
-
蛋白结构域
- N-Term
-
序列
- VQVETISPGD GRTFPKRGQT CVVHYTGMLE DGKKFDSSRD RNKPFKFMLG
-
产品特性
- This is a synthetic peptide designed for use in combination with anti-FKBP1A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
纯化方法
- Purified
-
-
-
-
应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
浓度
- 1 mg/mL
-
缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
-
背景
-
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.
Alias Symbols: FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PKCI2, PPIASE, FKBP-1A
Protein Interaction Partner: MTOR,TGFBR1,DHFR,FKBP1A,FKBP4,GLMN,ITPR1,MTOR,PPP3CA,PPP3R1,RYR1,RYR3,TGFB1I1,TGFBR1,TRPC3,YY1,ACVR1B,BMPR1A,DHFR,FKBP1A,GLMN,ITPR1,MTOR,Mtor,Mtor,RPTOR,RYR1,RYR3,SMAD7,TGFB1,TGFBR1,YY1
Protein Size: 108 -
分子量
- 12 kDa
-
基因ID
- 2280
-
NCBI登录号
- NM_000801, NP_000792
-
UniProt
- P62942
抗原
-
You are here:
