Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) (Middle Region) Peptide
FGR
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN976849
发货至:
中国
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Contact Info
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Quick Overview for Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) (Middle Region) Peptide (ABIN976849)
抗原
Fgr (FGR)
(Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- CPPGCPASLY EAMEQTWRLD PEERPTFEYL QSFLEDYFTS AEPQYQPGDQ
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产品特性
- This is a synthetic peptide designed for use in combination with anti-FGR Antibody(ARP54523_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR) peptide
FGR 适用: 人, 小鼠, 大鼠, 犬 宿主: 合成 BP, Imm
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Fgr (FGR) (Gardner-Rasheed Feline Sarcoma Viral (V-Fgr) Oncogene Homolog (FGR))
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背景
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This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alias Symbols: FLJ43153, MGC75096, SRC2, c-fgr, c-src2, p55c-fgr, p58c-fgr, p55-Fgr, p58-Fgr
Protein Interaction Partner: ARRB1,CBL,CCR3,CD24,CSK,DAB2,DOK1,FGR,HCLS1,INPP5D,PTK2,SLAMF1,SNCA,SRC,SYK,VDR,WAS,YWHAQ,CBL,CCR3,CD24,DAB2,DOK1,FASLG,HCLS1,IKBKG,NCOA6,PTK2,SLAMF1,SYK,WAS
Protein Size: 529 -
分子量
- 59 kDa
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基因ID
- 2268
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NCBI登录号
- NM_001042729, NP_001036194
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UniProt
- P09769
抗原
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