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Fibroblast Growth Factor 2 (Basic) (FGF2) (Middle Region) Peptide

FGF2 适用: 人 宿主: 合成 WB, BP, IHC
产品编号 ABIN976833
发货至: 中国
  • 抗原 See all FGF2 products
    FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 2
    合成
    应用范围
    Western Blotting (WB), Blocking Peptide (BP), Immunohistochemistry (IHC)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-FGF2 antibody (Catalog #: ARP42005_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
    别名
    BFGF Peptide, FGF-2 Peptide, FGFB Peptide, HBGF-2 Peptide, Fgf-2 Peptide, Fgfb Peptide, bFGF Peptide, fibroblast growth factor 2 Peptide, fibroblast growth factor 2 (basic) Peptide, FGF2 Peptide, Fgf2 Peptide, fgf2 Peptide
    背景
    The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors.The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: BFGF, FGFB, HBGF-2

    Protein Interaction Partner: NRP1,API5,CD44,CEP57,CSNK2A1,CSNK2A2,CSNK2B,CXCL13,FGF2,FGFBP1,FGFR1,FGFR3,FGFR4,FGFRL1,GPC3,GPC4,HSPG2,NRP1,PF4,PRMT1,PTX3,RPL6,RPS19,RPS6KA3,SDC1,SDC2,SDC3,VTN,CSNK2A1,CSNK2A2,CSNK2B,FGFBP1,FGFR1,GPC3,GPC4,RPL6,RPS19,SDC1,SDC2,SDC3,SDC4,VTN

    Protein Size: 288
    分子量
    31 kDa
    基因ID
    2247
    NCBI登录号
    NM_002006, NP_001997
    UniProt
    P09038
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