FYVE, RhoGEF and PH Domain Containing 1 (FGD1) Peptide
FGD1
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all FGD1 products
- FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-FGD1 antibody (Catalog #: ARP38472_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
- 别名
- AAS Peptide, FGDY Peptide, MRXS16 Peptide, ZFYVE3 Peptide, FYVE, RhoGEF and PH domain containing 1 Peptide, FGD1 Peptide, Fgd1 Peptide, fgd1 Peptide
- 背景
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FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AAS, FGDY, ZFYVE3, MRXS16
Protein Interaction Partner: ABP1,CDC42,CTTN,ELMO1,CDC42
Protein Size: 961 - 分子量
- 106 kDa
- 基因ID
- 2245
- NCBI登录号
- NM_004463, NP_004454
- UniProt
- P98174
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