FYVE, RhoGEF and PH Domain Containing 1 (FGD1) Peptide
FGD1
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN976823
发货至:
中国
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Contact Info
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中国
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Quick Overview for FYVE, RhoGEF and PH Domain Containing 1 (FGD1) Peptide (ABIN976823)
抗原
FGD1
(FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-FGD1 antibody (Catalog #: ARP38472_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
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背景
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FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AAS, FGDY, ZFYVE3, MRXS16
Protein Interaction Partner: ABP1,CDC42,CTTN,ELMO1,CDC42
Protein Size: 961 -
分子量
- 106 kDa
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基因ID
- 2245
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NCBI登录号
- NM_004463, NP_004454
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UniProt
- P98174
抗原
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