F-Box and WD Repeat Domain Containing 2 (FBXW2) (Middle Region) Peptide
FBXW2
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN976768
发货至:
中国
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Contact Info
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中国
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Quick Overview for F-Box and WD Repeat Domain Containing 2 (FBXW2) (Middle Region) Peptide (ABIN976768)
抗原
FBXW2
(F-Box and WD Repeat Domain Containing 2 (FBXW2))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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产品特性
- This is a synthetic peptide designed for use in combination with anti-FBXW2 antibody (Catalog #: ARP43109_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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F-Box and WD Repeat Domain Containing 2 (FBXW2) peptide
FBXW2 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig 宿主: 合成 BP, Imm
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FBXW2 (F-Box and WD Repeat Domain Containing 2 (FBXW2))
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背景
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F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. FBXW2 is the second identified member of the F-box family and contains multiple WD-40 repeats.F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats.
Alias Symbols: FBW2, Fwd2, MGC117371, Md6
Protein Interaction Partner: SKP1,SKP1,SKP1,CUL1,SKP1,CDC34,CUL1,SKP1,UBE2D2
Protein Size: 454 -
分子量
- 51 kDa
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基因ID
- 26190
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NCBI登录号
- NM_012164, NP_036296
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UniProt
- Q9UKT8
抗原
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