F-Box and WD Repeat Domain Containing 11 (FBXW11) Peptide
FBXW11
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN976767
发货至:
中国
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Contact Info
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中国
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北京 101111
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Quick Overview for F-Box and WD Repeat Domain Containing 11 (FBXW11) Peptide (ABIN976767)
抗原
FBXW11
(F-Box and WD Repeat Domain Containing 11 (FBXW11))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-FBXW11 antibody (Catalog #: ARP43379_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))
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背景
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FBXW11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.
Alias Symbols: BTRC2, BTRCP2, FBW1B, FBXW1B, Fbw11, Hos, KIAA0696
Protein Interaction Partner: BTRC,CDC25A,CUL1,FBXW11,GLI2,IFNAR1,NFKB1,NFKBIA,WEE1,ARIH1,ATG4B,BTRC,CDC25B,CLPX,CLSPN,CUL1,FAM123B,FBXW11,HIVEP1,HIVEP2,KHDRBS2,MYO10,NFKBIA,NRD1,NUDC,OGT,PDCD4,RPRM,SKP1,SUN2,TFAP4,TUBGCP3,USP37,USP47,WEE1,ZRANB1
Protein Size: 529 -
分子量
- 61 kDa
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基因ID
- 23291
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NCBI登录号
- NM_033644, NP_387448
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UniProt
- Q9UKB1
抗原
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