Coagulation Factor XI (F11) (C-Term) Peptide
F11
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all Factor XI (F11) products
- Factor XI (F11) (Coagulation Factor XI (F11))
- 蛋白结构域
- C-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- RHLCGGSIIG NQWILTAAHC FYGVESPKIL RVYSGILNQS EIKEDTSFFG
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-F11 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- Factor XI (F11) (Coagulation Factor XI (F11))
- 背景
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This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.
Alias Symbols: FXI, MGC141891
Protein Interaction Partner: F11,F2,HGF,KNG1,SERPINA5,SERPINF2,TFPI2,KNG1,SERPINA5
Protein Size: 625 - 分子量
- 70 kDa
- 基因ID
- 2160
- NCBI登录号
- NM_000128, NP_000119
- UniProt
- P03951
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