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Epithelial Splicing Regulatory Protein 2 (ESRP2) (C-Term) Peptide

ESRP2 适用: 小鼠 宿主: 合成 BP, WB
产品编号 ABIN976446
发货至: 中国
  • 抗原 See all ESRP2 products
    ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))
    蛋白结构域
    C-Term
    宿主
    小鼠
    资源
    • 6
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    LLPAARVPAA ATPLAYYPGP ATQLYMNYTA YYPSPPVSPT TVGYLTTPPT
    产品特性
    This is a synthetic peptide designed for use in combination with anti-Esrp2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))
    别名
    RBM35B Peptide, 9530027K23Rik Peptide, Rbm35b Peptide, RGD1310855 Peptide, cb404 Peptide, fa07a06 Peptide, rbm35b Peptide, sb:cb404 Peptide, zgc:77254 Peptide, epithelial splicing regulatory protein 2 Peptide, microRNA 6773 Peptide, ESRP2 Peptide, Esrp2 Peptide, MIR6773 Peptide, esrp2 Peptide
    背景
    Esrp2 is an mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. It specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. It also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). It acts by directly binding specific sequences in mRNAs and binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.

    Alias Symbols: 9530027K23Rik, Rbm35b

    Protein Size: 717
    分子量
    77 kDa
    基因ID
    77411
    NCBI登录号
    NM_176838, NP_789808
    UniProt
    Q8K0G8
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