Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15) Peptide
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Quick Overview for Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15) Peptide (ABIN976395)
抗原
宿主
资源
应用范围
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产品特性
- This is a synthetic peptide designed for use in combination with anti-EPS15 antibody (Catalog #: ARP54601_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
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背景
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EPS15 is a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias.This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AF-1P, AF1P, MLLT5
Protein Interaction Partner: AGFG1,AGFG2,CDC40,EPN2,EPN2,NUMB,NUMBL,RNF11,SH3BP4,AGFG1,AGFG2,AP2A1,AP2A2,CRK,DNM1,DNM2,EGFR,ELF3,EPN1,EPN2,EPS15,HGS,ITSN1,LAPTM5,MOBKL3,NAGPA,NEDD4,NUMB,NUMBL,REPS2,RNF11,SNAP91,SPG20,STAM2,STAMBP,STON2,SYNJ1,UBB,UBQLN1,AGFG1,AGFG2,AP2A1,AP2A2,CLINT1,CRK,DNM2,EGFR,EPN1,GRB2,HGS,NAGPA,RAB11FIP2,REPS2,RNF11,SCAMP1,SLC6A3,SNAP91,STAM2,STON2,Synj1,UBE2D1,UBE2D2,UBE2D3,UBE2E1,UBE2H
Protein Size: 896 -
分子量
- 99 kDa
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基因ID
- 2060
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NCBI登录号
- NM_001981, NP_001972
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UniProt
- P42566
抗原
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