E74 like ETS transcription factor 4 (Elf4) Peptide
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Quick Overview for E74 like ETS transcription factor 4 (Elf4) Peptide (ABIN976283)
抗原
宿主
资源
应用范围
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产品特性
- This is a synthetic peptide designed for use in combination with anti-ELF4 antibody (Catalog #: ARP32248_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Elf4 (E74 like ETS transcription factor 4 (Elf4))
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背景
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ELF4 contains 1 ETS DNA-binding domain and belongs to the ETS family. It is transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. It transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. It acts synergistically with RUNX1 to transactivate the IL3 promoter and also transactivates the PRF1 promoter in natural killer (NK) cells. ELF4 plays a role in the development and function of NK and NK T-cells and in innate immunity.
Alias Symbols: ELFR, MEF
Protein Interaction Partner: FBXO4,FBXO7,PML,RUNX1,SKP2,UBB,RUNX1
Protein Size: 663 -
分子量
- 71 kDa
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基因ID
- 2000
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NCBI登录号
- NM_001421, NP_001412
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UniProt
- Q99607
抗原
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