Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) (N-Term) Peptide
EIF4G2
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all EIF4G2 products
- EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-EIF4G2 antibody (Catalog #: ARP40362_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))
- 别名
- AAG1 Peptide, DAP5 Peptide, NAT1 Peptide, P97 Peptide, NAT1B Peptide, eif4g2 Peptide, hm:zeh1307 Peptide, wu:fa14h01 Peptide, wu:fb44h01 Peptide, wu:fb59c06 Peptide, wu:fc21b05 Peptide, EIF4G2 Peptide, AA589388 Peptide, DAP-5 Peptide, E130105L11Rik Peptide, Nat1 Peptide, Natm1 Peptide, p97 Peptide, NAT1A Peptide, im:7148615 Peptide, wu:fb81f07 Peptide, wu:fb82b06 Peptide, wu:fb98h08 Peptide, dap5 Peptide, eif4g2.L Peptide, nat1 Peptide, eukaryotic translation initiation factor 4 gamma 2 Peptide, eukaryotic translation initiation factor 4, gamma 2b Peptide, eukaryotic translation initiation factor 4, gamma 2 Peptide, eukaryotic translation initiation factor 4 gamma, 2 Peptide, eIF4G-related protein NAT1 Peptide, eukaryotic translation initiation factor 4, gamma 2a Peptide, eukaryotic translation initiation factor 4 gamma, 2 S homeolog Peptide, EIF4G2 Peptide, eif4g2b Peptide, Eif4g2 Peptide, nat1 Peptide, eif4g2a Peptide, eif4g2.S Peptide
- 背景
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Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. EIF4G2 shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3, eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, EIF4G2 functions as a general repressor of translation by forming translationally inactive complexes. Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3, eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
Alias Symbols: AAG1, DAP5, FLJ41344, NAT1, p97, P97
Protein Interaction Partner: NCBP1,CASP3,EIF2S2,EIF3A,EIF4A1,EIF4A2,EIF4E,EIF5,MKNK1,NCBP1,SKIL,EIF3A,EIF3F,EIF4A1,EIF4A2,EIF4E,MAGEA6,MKNK1
Protein Size: 907 - 分子量
- 102 kDa
- 基因ID
- 1982
- NCBI登录号
- NM_001418, NP_001409
- UniProt
- P78344
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