Early Growth Response 4 (EGR4) Peptide
EGR4
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all EGR4 products
- EGR4 (Early Growth Response 4 (EGR4))
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-EGR4 antibody (Catalog #: ARP38090_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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Early Growth Response 4 (EGR4) peptide
EGR4 适用: 人 宿主: 合成 BP, Imm
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- EGR4 (Early Growth Response 4 (EGR4))
- 别名
- EGR4 Peptide, NGFI-C Peptide, NGFIC Peptide, PAT133 Peptide, NGF1-C Peptide, pAT133 Peptide, Egr4l1 Peptide, early growth response 4 Peptide, EGR4 Peptide, Egr4 Peptide
- 背景
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The nerve growth factor-induced clone C (NGFI-C/EGR4) gene is a zinc-finger transcription factor that is rapidly induced by nerve growth factor in rat pheochromocytoma PC12 cells and by seizure in brain. NGFI-C/EGR4 is closely related to the previously described early response genes, nerve growth factor-induced clone A (NGFI-A or EGR1), EGR2, and EGR3. These four early response (immediate early) proteins all contain very similar zinc-finger DNA binding domains and five highly homologous subdomains. EGR-4 functionally cooperate with NFAT proteins and induce expression of IL-2 and TNFalpha. Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.
Alias Symbols: NGFIC, NGFI-C, PAT133
Protein Interaction Partner: NFATC2
Protein Size: 486 - 分子量
- 51 kDa
- 基因ID
- 1961
- NCBI登录号
- NM_001965, NP_001956
- UniProt
- Q05215
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