Epidermal Growth Factor Receptor (EGFR) (Middle Region) Peptide
EGFR
适用: 人
宿主: 合成
BP, WB
Quick Overview for Epidermal Growth Factor Receptor (EGFR) (Middle Region) Peptide (ABIN976174)
抗原
EGFR
(Epidermal Growth Factor Receptor (EGFR))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
-
-
蛋白结构域
- Middle Region
-
序列
- VTDHGSCVRA CGADSYEMEE DGVRKCKKCE GPCRKVCNGI GIGEFKDSLS
-
产品特性
- This is a synthetic peptide designed for use in combination with anti-EGFR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
纯化方法
- Purified
-
-
-
-
应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
浓度
- 1 mg/mL
-
缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- EGFR (Epidermal Growth Factor Receptor (EGFR))
-
背景
-
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
Alias Symbols: ERBB, ERBB1, HER1, PIG61, mENA
Protein Interaction Partner: CALM1,CD44,CDH1,EGF,EGFR,ERBB2,GRB2,HSP90AA1,MUC1,PAK1,PIK3R1,PIK3R2,PLCG1,PLD2,RASA1,SHC1,SHC1,SHC1,STAT3,VAV2,ACTA1,ADRBK1,AGTR1,ALCAM,AMH,ANXA1,AR,AREG,ARF4,ATP1A1,ATP1B1,ATP5C1,BTC,CALM1,CALM3,CALM3,CAMK2A,CAMK2G,CAMLG,CASP1,CAV1,CAV2,CAV3,CBL,CBLB,CB
Protein Size: 628 -
分子量
- 69 kDa
-
基因ID
- 1956
-
NCBI登录号
- NM_201282, NP_958439
-
UniProt
- P00533
抗原
-
You are here:
