Deltex Homolog 2 (DTX2) Peptide
DTX2
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all DTX2 products
- DTX2 (Deltex Homolog 2 (DTX2))
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-DTX2 antibody (Catalog #: ARP43285_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- DTX2 (Deltex Homolog 2 (DTX2))
- 背景
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DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. DTX2 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context and mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. It also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Alias Symbols: KIAA1528, MGC71098, RNF58
Protein Interaction Partner: DTX1,DTX2,DTX3,HPCAL1,HPCAL4,NCALD,NCS1,NOTCH1,PLSCR1,RBPMS,RFX6,RHOXF2,TRIP13,UBE2D4,UBQLN4,VSNL1,HPCAL1,HPCAL4,NCALD,NCS1,PLSCR1,RBPMS,RFX6,RHOXF2,SFN,TRIP13,UBE2D4,VSNL1
Protein Size: 575 - 分子量
- 62 kDa
- 基因ID
- 113878
- NCBI登录号
- NM_001102596, NP_001096066
- UniProt
- Q6XM87
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