Deoxynucleotidyltransferase, terminal (DNTT) Peptide
DNTT
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all TdT (DNTT) products
- TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-DNTT antibody (Catalog #: ARP52031_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
- 别名
- TdT Peptide, TDT Peptide, BB160593 Peptide, Tdt Peptide, dntt-A Peptide, dntt Peptide, DNA nucleotidylexotransferase Peptide, deoxynucleotidyltransferase, terminal Peptide, DNA nucleotidylexotransferase L homeolog Peptide, terminal deoxynucleotidyl transferase Peptide, DNTT Peptide, dntt Peptide, Dntt Peptide, dntt.L Peptide, tdt Peptide
- 背景
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DNTT is a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, DNTT is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
Alias Symbols: TDT
Protein Interaction Partner: DNTTIP1,DNTTIP2,PCNA,PRPF19,XRCC6,ABTB2,CUL3,DNTTIP2,PCNA,PRPF19,UBC,XRCC6
Protein Size: 509 - 分子量
- 58 kDa
- 基因ID
- 1791
- NCBI登录号
- NM_004088, NP_004079
- UniProt
- P04053
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