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Deoxyribonuclease II beta (DNASE2B) (Middle Region) Peptide

DNASE2B 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN975930
发货至: 中国
  • 抗原 See all DNASE2B products
    DNASE2B (Deoxyribonuclease II beta (DNASE2B))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 7
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-DNASE2B antibody (Catalog #: ARP42597_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    DNASE2B (Deoxyribonuclease II beta (DNASE2B))
    背景
    DNASE2B shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH . Unlike DNase II which is ubiquitously expressed, expression of this protein is restricted to the salivary gland and lungs. The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH . Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene.

    Alias Symbols: DLAD

    Protein Size: 153
    分子量
    18 kDa
    基因ID
    58511
    NCBI登录号
    NM_058248, NP_490649
    UniProt
    Q5VXD0
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