Deleted in Malignant Brain Tumors 1 (DMBT1) (N-Term) Peptide
DMBT1
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN975861
发货至:
中国
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Contact Info
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Quick Overview for Deleted in Malignant Brain Tumors 1 (DMBT1) (N-Term) Peptide (ABIN975861)
抗原
DMBT1
(Deleted in Malignant Brain Tumors 1 (DMBT1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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序列
- SWSTPSPDTL PTITLPASTV GSESSLALRL VNGGDRCQGR VEVLYRGSWG
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产品特性
- This is a synthetic peptide designed for use in combination with anti-DMBT1 Antibody(ARP42352_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))
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背景
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Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. The gene DMBT1 was originally isolated based on its deletion in a medulloblastoma cell line. DMBT1 is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The DMBT1 protein is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor supressor gene, but rather play a role in the interaction of tumor cells and the immune system.
Alias Symbols: GP340, MGC164738, muclin
Protein Interaction Partner: SFTPA1,SFTPD,SFTPA1,SFTPD
Protein Size: 2413 -
分子量
- 258 kDa
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基因ID
- 1755
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NCBI登录号
- NM_007329, NP_015568
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UniProt
- Q9UGM3
抗原
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