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Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1) Peptide

DEAF1 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN975713
发货至: 中国
  • 抗原 See all DEAF1 products
    DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))
    宿主
    资源
    • 2
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-DEAF1 antibody (Catalog #: ARP39467_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))
    别名
    AU042387 Peptide, C230009B13Rik Peptide, NUDR Peptide, SPN Peptide, ZMYND5 Peptide, MYND5 Peptide, spn Peptide, DEAF1 Peptide, nudr Peptide, zmynd5 Peptide, CG8567 Peptide, DEAF-1 Peptide, Deaf-1 Peptide, Dmel\\CG8567 Peptide, deaf1 Peptide, l(3)76BDv Peptide, deformed epidermal autoregulatory factor 1 (Drosophila) Peptide, DEAF1, transcription factor Peptide, DEAF1 transcription factor Peptide, deformed epidermal autoregulatory factor 1 homolog Peptide, Deformed epidermal autoregulatory factor-1 Peptide, Deaf1 Peptide, DEAF1 Peptide, LOC509260 Peptide, deaf1 Peptide, deaf-1 Peptide
    背景
    DEAF1 down-regulates transcription of those genes by binding to sequence with multiple copies of TTC[CG]G present in their own promoter and that of the HNRPA2B1 gene. DEAF1 binds to the retinoic acid response element (RARE) AGGGTTCACCGAAAGTTCA. DEAF1 activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase.

    Alias Symbols: NUDR, SPN, ZMYND5

    Protein Interaction Partner: DEAF1,ASCC2,INTS1,ASCC2,LMO4

    Protein Size: 565
    分子量
    59 kDa
    基因ID
    10522
    NCBI登录号
    NM_021008, NP_066288
    UniProt
    O75398
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