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Dishevelled Associated Activator of Morphogenesis 1 (DAAM1) (Middle Region) Peptide

DAAM1 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN975574
发货至: 中国
  • 抗原 See all DAAM1 products
    DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 2
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-DAAM1 antibody (Catalog #: ARP55131_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    DAAM1 (Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))
    别名
    1700066F09Rik Peptide, 2310028E21Rik Peptide, AI503486 Peptide, E130308H01 Peptide, mKIAA0666 Peptide, daam-1 Peptide, xdaam1 Peptide, daam1 Peptide, DAAM1 Peptide, DKFZp468D0524 Peptide, daam1l Peptide, fc83b10 Peptide, si:ch211-87i20.1 Peptide, wu:fc83b10 Peptide, dishevelled associated activator of morphogenesis 1 Peptide, dishevelled associated activator of morphogenesis 1 S homeolog Peptide, dishevelled associated activator of morphogenesis 1a Peptide, dishevelled associated activator of morphogenesis 1b Peptide, DAAM1 Peptide, Daam1 Peptide, daam1.S Peptide, daam1a Peptide, daam1 Peptide, daam1b Peptide
    背景
    Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein.Functions of the cell cortex, including motility, adhesion, and cytokinesis, are mediated by the reorganization of the actin cytoskeleton and recent evidence suggests a role for the Formin homology (FH) proteins in these processes. The protein encoded by this gene contains FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. Wnt/Fz signaling activates the small GTPase Rho, a key regulator of cytoskeleton architecture, to control cell polarity and movement during development. Activation requires Dvl-Rho complex formation, an assembly mediated by this gene product, which is thought to function as a scaffolding protein. Evidence of alternative splicing has been observed for this gene but the full-length nature of these variants has not been determined.

    Alias Symbols: FLJ41657, KIAA0666

    Protein Interaction Partner: DVL1,DVL2,RHOA

    Protein Size: 1078
    分子量
    123 kDa
    基因ID
    23002
    NCBI登录号
    NM_014992, NP_055807
    UniProt
    Q9Y4D1
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